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With consistent B12 injection, you are essentially supporting the nerve cells optimal function

Your concentration drops to 1 mg/mL

Additionally, transportation was a problem

Without human trial data, clinicians and patients are making decisions based on incomplete information, and the self-reported adverse effect profile anxiety, palpitations, insomnia, fatigue is not benign enough to ignore

The downstream effects most consistently described in the literature: induction of collagen I and III, elastin, and decorin synthesis (Maquart et al., FEBS Letters , 1988), upregulation of VEGF and basic FGF transcripts, induction of antioxidant defense genes including SOD2 and metallothionein isoforms, and modulation of the MMP-2 and TIMP-1/2 balance toward non-fibrotic remodeling